Signatera™
Transforming the management of cancer with personalized testing
Signatera is a personalized, tumor-informed assay optimized to detect circulating tumor DNA (ctDNA) for molecular residual disease (MRD) assessment and recurrence monitoring for patients previously diagnosed with cancer, with broad utility for cancer management.
Knowing earlier matters
Each person’s cancer is as unique as their fingerprint. Signatera is a new blood test that is personalized to each patient’s set of tumor mutations and can identify earlier than traditional tools if cancer is still present. Knowing this information can help you have a more informed discussion with your doctor regarding your treatment journey.

Watch Scott’s story about how Signatera plays a role in his cancer management
Scott Jones
Signatera Patient
Signatera is validated in multiple cancer types

I have colorectal cancer
If you have been diagnosed with colorectal cancer, learn more how to identify residual disease and detect relapse sooner

I am on immunotherapy
If you are undergoing immunotherapy and want to know how Signatera can help monitor the effectiveness of your treatment

Is Signatera right for me?
If you have been diagnosed with cancer such as breast, ovarian, lung or melanoma and want to learn more how to identify residual disease and detect relapse sooner
Why Signatera?
Signatera is a blood test used for cancer detection and surveillance. It is personalized for each patient.
A doctor may order Signatera along with routine follow-up exams to determine whether:
- There are signs of cancer remaining in the body
- Treatment (e.g., chemotherapy, radiation) is working
- The cancer is recurring
How Signatera Works: a personalized and tumor informed approach to MRD surveillance

A one-time analysis of both blood and tissue determines your unique set of tumor mutations.

The test is custom-built and personalized for you.

Signatera detects the presence or absence of cancer each time it is ordered as part of your routine follow-up blood tests.
Understanding your Signatera test results
If you have metastatic cancer, a negative result may mean that your treatment was able to decrease the amount of cancer cells to undetectable levels, meaning the treatment has been effective.