Skip navigation

Vistara Single-Gene NIPT

Vistara is the most comprehensive prenatal single-gene screening test for serious genetic conditions. These conditions affect quality of life, could benefit from early intervention, or could otherwise go undetected.
Vistara tests for 25 serious genetic conditions with a blood draw from the mother. Most results will be returned to your clinician within 2-3 weeks.

Vistara is the next evolution in NIPT, going beyond chromosomal conditions to single-gene disorders

Vistara is the next evolution in NIPT

Screened Conditions Include

  • Noonan syndrome
  • Achondroplasia
  • Osteogenesis imperfecta
  • Rett syndrome
  • And 21 other single-gene disorders across 30 genes
Vistara Chart Incidence at Birth

Conditions screened by Vistara have a combined incidence of 1 in 600 – higher than that of Down syndrome for pregnancies in women under 32.


No errors detected in clinical validation

Vistara’s clinical validation published in Nature Medicine showed the following performance metrics:2

  • >99% sensitivity
  • >99% specificity


Commercial experience has also shown no known false positives.4

Consider Vistara for:


Women who want to know as much as possible, non-invasively


Couples with male partner over 35 – 40-years-old (advanced paternal age)


Ultrasound anomalies including increased nuchal translucency and shortened long bones


Family history of hereditary conditions


Vistara can be a beneficial adjunct to traditional prenatal diagnostic procedures like chorionic villus sampling (CVS) and amniocentesis

  • One of the most comprehensive Noonan panels available
  • Screens for conditions not included in standard diagnostic microarray
  • Findings on Vistara can be confirmed using the same original diagnostic sample, additional confirmatory procedures are not needed*

*Cells must be saved for additional diagnostic testing


1Snijders, et al. Ultrasound Obstet Gynecol 1999;13:167-170.

2Zhang J et al. Nat Med. 2019 Mar;25(3):439-447.

3Pagon RA et al., editors. GeneReviews® [Internet]. Seattle (WA): University of Washington, Seattle; 1993-2017.

4Natera internal data on file.

Is Vistara right for you?

We’re here to help you find out