Proven to boost IVF success
Spectrum preimplantation genetic testing (PGT) evaluates embryos for extra or missing chromosomes (PGT-A), single gene conditions (PGT-M), or structural rearrangements (PGT-SR), improving the chances of a healthy pregnancy.
Spectrum tests for chromosomal abnormalities and known inherited genetic condition(s). Sample collections include an embryo biopsy and parental blood/cheek swab. Most results will be returned to your doctor within 5-7 business days.
What is PGT-A and PGT-M?
PGT-A and PGT-M can improve the chance of a healthy pregnancy
PGT-A is a type of embryo screening that identifies embryos with extra or missing chromosomes, also called aneuploidy. For couples undergoing in vitro fertilization (IVF), identifying these embryos is important when selecting embryos for transfer.
For individuals who know they are carriers of a single gene condition and are at risk for passing the condition on to their children, PGT-M can help identify unaffected embryo(s) for transfer.
Why choose Spectrum?
Spectrum provides the most comprehensive PGT available. Across a range of maternal ages, pregnancy rates are higher when Spectrum is performed with IVF.
Spectrum’s PGT is performed using a SNP array method and can:
- Increase the chance of embryo implantation
- Decrease the chance of miscarriage
- Reduce the time to pregnancy
- Reduce the chance of having a child with a chromosomal abnormality or single gene condition.
Spectrum is the only PGT that confirms parentage. Natera’s Parental SupportTM technology uses genetic information from the parents to automatically confirm that the embryo samples match the parental samples.
The Spectrum process
PGT requires embryo biopsy, the removal of either a single or a small number of cells from a growing embryo. This procedure can be performed on day 3 of an IVF cycle after egg retrieval, or more commonly, on days 5-7 when embryos reach the blastocyst stage of development.
The Spectrum embryo testing process is completed in conjunction with an IVF cycle:
- Eggs are fertilized and allowed to grow and develop into embryos.
- A biopsy performed with each of the developing embryos.
- Each embryo remains at the IVF center and is cryopreserved, while biopsy samples are shipped to Natera.
- The samples are analyzed by Natera and Spectrum results are sent to your IVF center.
- Your physician determines which embryo (if any) is optimal for transfer to the uterus.
A blood, cheek, or sperm sample is required from BOTH the egg and sperm contributors in addition to the biopsy samples. Family member samples may also be requested for PGT-M. Mobile phlebotomy services and local blood draw sites are available to help with the blood draw.