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August 8, 2018

Natera Reports Second Quarter 2018 Financial Results

SAN CARLOS, Calif., Aug. 8, 2018 /PRNewswire/ — Natera, Inc. (NASDAQ:  NTRA), a leader in non-invasive genetic testing and the analysis of circulating cell-free DNA, today reported financial results for the second quarter ended June 30, 2018 and provided an update on recent business progress.

Natera, Inc. Logo (PRNewsFoto/Natera, Inc.)

Recent Accomplishments & Highlights

  • Generated total revenues of $63.1 million in the second quarter of 2018 compared to $52.3 million in the second quarter of 2017, an increase of 21%.
  • Processed 162,807 tests in the second quarter of 2018, compared to approximately 125,700 tests processed in the second quarter of 2017, an increase of approximately 29%.
  • Processed approximately 113,300 Panorama tests in the second quarter of 2018, compared to approximately 89,400 Panorama tests processed in the second quarter of 2017, an increase of approximately 27%.
  • Accessioned approximately 41,800 Horizon carrier screening (HCS) tests in the second quarter of 2018 compared to approximately 30,700 Horizon carrier screening tests accessioned in the second quarter of 2017, an increase of approximately 36%.  
  • After the close of the quarter, Natera successfully completed a secondary equity offering of 5,175,000 shares priced at $20 per share and raised $97.3 million in net proceeds, which included shares sold upon the exercise of the underwriters’ over-allotment option.
  • Announced development of powerful kidney transplant rejection marker in a study with the University of CaliforniaSan Francisco that demonstrated superior performance of Natera’s mmPCR technology for detecting acute rejection in kidney transplant patients.
  • Published results from a clinical validation study of a new biomarker for pregnancy management that relies on Natera’s proprietary fetal fraction based algorithm to identify pregnancies at high risk for fetal abnormalities that may not otherwise be detected with available cell free DNA tests for fetal aneuploidies.
  • Announced that Natera has now signed agreements for 20 trials with leading pharmaceutical companies for the use of Signatera in oncology efforts.
  • Appointed Dr. Roy Baynes, Chief Medical Officer at Merck and SVP and head of Global Clinical Development at Merck Research Laboratories, to Natera’s board of directors.  

"We were very pleased to present excellent results in our kidney transplant study with UCSF, deepen our oncology expertise with the addition of Dr. Baynes to our board, and publish a clinical validation study that we believe extends our technology leadership in NIPT," said Matt Rabinowitz, Natera’s Chief Executive Officer. "The completion of our follow-on equity offering gives us capital to pursue near term opportunities across prenatal health, transplant rejection, and oncology."

Second Quarter Ended June 30, 2018 Financial Results

Total revenues were $63.1 million compared to $52.3 million for the second quarter of 2017, an increase of 21% over the same period in 2017. Effective January 1, 2018, we adopted the new revenue recognition guidance under Accounting Standards Codification Topic 606 (ASC 606) using the full retrospective approach. Natera processed 162,807 tests in the second quarter of 2018, including approximately 152,500 tests accessioned and 9,500 processed through the Constellation software platform (Constellation units), compared to approximately 125,700 tests processed in the second quarter of 2017, including approximately 118,700 tests accessioned and 7,000 Constellation units, an overall increase of approximately 29%.

In the three months ended June 30, 2018, Natera recognized revenue on 155,100 tests for which results were reported to customers in the period (tests reported), including approximately 145,900 tests accessioned and 9,200 Constellation units, compared to 119,300 tests reported, including approximately 112,500 tests accessioned and 6,800 Constellation units, in the second quarter of 2017, which represents an increase in tests reported of approximately 30%. Natera recognized revenues on approximately 103,200 Panorama tests accessioned and 7,600 Panorama Constellation units in the three months ended June 30, 2018, compared to approximately 80,000 Panorama tests accessioned and 5,200 Panorama Constellation units in the same period in 2017. Natera recognized revenue on approximately 38,700 HCS tests accessioned in the three months ended June 30, 2018, compared to approximately 29,100 HCS tests accessioned in the same period in 2017.      

Gross profit for the three months ended June 30, 2018 was $22.1 million, representing a 35% gross margin, compared to $17.7 million, representing a 34% gross margin in the same period of the prior year.* The improvement in gross margin was primarily due to increased revenues recognized from our Panorama and HCS tests, continued cost savings resulting from streamlined workflows under Version 3 of Panorama, and our updated in-house HCS automation workflow launched in April 2018.

Total operating expenses, representing research and development expenses and selling, general and administrative expenses, for the second quarter of 2018 were $49.3 million, an increase of approximately 7% compared to $46.1 million in the same period of the prior year. The increase was driven primarily by higher corporate-related expenses incurred due to increased collection efforts and certain regulatory filings, higher stock-based compensation expense, and an increase in external services costs.

Loss from operations for the second quarter of 2018 was $27.2 million compared to $28.4 million for the same period of the prior year.

Net loss for the second quarter of 2018 was $33.8 million, or ($0.62) per diluted share, compared to net loss of $29.1 million, or $(0.55) per diluted share for the same period in 2017. Excluding the impact of $4.0 million attributable to the change in the fair value of a warrant liability related to a 2013 senior secured term loan that has since been repaid, net loss for the second quarter of 2018 was $(0.55) per diluted share, on a non-GAAP basis. Weighted average shares outstanding were 54.6 million in the second quarter of 2018.

At June 30, 2018, Natera held $89.2 million in cash, cash equivalents, short-term investments and restricted cash, compared to $119.7 million as of March 31, 2018. As of June 30, 2018, Natera had a total outstanding debt balance of $123.3 million, comprised of $50.1 million with accrued interest under its $50.0 million line of credit with UBS at a variable interest rate of 30-day LIBOR plus 110 bps and a net carrying amount of $73.2 million under its $100.0 million debt facility with OrbiMed Advisors, compared to $50.1 million with accrued interest and the net carrying amount of $73.1 million as of March 31, 2018. The UBS line of credit is secured by Natera’s investment portfolio, which is designed to yield higher returns than the borrowing rate Natera incurs in order to fund current operations. The debt facility with OrbiMed Advisors is secured by substantially all of Natera’s assets, including its intellectual property, subject to certain customary exclusions.

2018 Financial Outlook

Natera anticipates 2018 total revenue of $250 million to $275 million**; 2018 cost of revenues to be approximately 60% to 65% of revenues; selling, general and administrative costs to be approximately $140 million to $150 million; research and development costs to be approximately $50 million to $55 million, and net cash burn to be approximately $40 million to $60 million***.

* Gross profit is calculated as GAAP total revenues less GAAP cost of revenues. Gross margin is calculated as gross profit divided by GAAP total revenues.

**Our 2018 revenue guidance is based on the new revenue recognition guidance, ASC 606, which was effective for us in the first quarter of 2018.

*** Cash burn is calculated as the sum of GAAP net cash used by operating activities (estimated for 2018 to be between $35 million and $55 million) and GAAP net purchases of property and equipment (estimated for 2018 to be approximately $5 million).

About Natera

Natera is a genetic testing company that develops and commercializes non-invasive methods for analyzing DNA. The mission of the company is to transform the diagnosis and management of genetic disease. Natera operates an ISO 13485-certified and CAP-accredited laboratory certified under the Clinical Laboratory Improvement Amendments (CLIA) in San Carlos, Calif. It offers a host of proprietary genetic testing services to inform physicians who manage pregnant women, researchers in cancer including biopharmaceutical companies, and genetic laboratories through its cloud-based Constellation software platform.

Product offerings include Spectrum®, a preimplantation genetic test for embryo selection during in vitro fertilization (IVF); Anora® to understand the genetic causes of a pregnancy loss; Horizon to detect risk of inherited mutations such as cystic fibrosis and spinal muscular atrophy; Panorama®, a non-invasive pregnancy test (NIPT) to screen for common chromosomal anomalies in a fetus as early as nine weeks of gestation; Vistara to screen for single-gene disorders that represent total incidence greater than Down syndrome; Evercord, a cord blood and tissue banking service offered at birth to expectant parents; and Signatera (RUO), a personalized cell-free DNA test that can identify minimal residual disease, treatment response, and cancer recurrence to aid researchers in oncology.

Each test described above except Signatera (RUO) has been developed and its performance characteristics determined by the CLIA-certified laboratory performing the test. These tests have not been cleared or approved by the U.S. Food and Drug Administration (FDA). Although FDA does not currently clear or approve laboratory-developed tests in the U.S., certification of the laboratory is required under CLIA to ensure the quality and validity of the tests. Signatera is for research use only at this time.

Conference Call Information


Natera’s Second Quarter 2018 Results Conference Call 


Wednesday, August 8, 2018 


1:30 p.m. PT (4:30 p.m. ET)

Live Dial-In: 

(877) 823-0171, Domestic 

(617) 500-6932, International

Conference ID:



A webcast replay will be available at

Forward-Looking Statements

This release contains forward-looking statements, including quotations of management, statements under the heading "2018 Financial Outlook," and statements regarding Natera’s current and new products and services, commercial partners, user experience, clinical trials, future financial outlook and financial performance, opportunities and strategies, and general business conditions. Any forward-looking statements contained in this release are based upon Natera’s current plans, estimates, and expectations, as of the date of this release, and are not a representation that such plans, estimates, or expectations will be achieved. Subsequent events may cause these expectations to change, and Natera disclaims any obligation to update the forward-looking statements in the future.

These forward-looking statements are subject to known and unknown risks and uncertainties that may cause actual results to differ materially, including: we face numerous uncertainties and challenges in achieving the financial guidance provided; we derive most of our revenues from Panorama, and if our efforts to further increase the use and adoption of Panorama or to develop and commercialize new products and services in the future do not succeed, our business will be harmed; we have incurred losses since our inception and we anticipate that we will continue to incur losses for the foreseeable future; uncertainty in the development and commercialization of our enhanced or new tests or services, for example if the results of our clinical studies do not support the use of our tests, could materially adversely affect our business, financial condition and results of operations; our quarterly results may fluctuate significantly; we may be unable to compete successfully with either existing or future products or services; our cloud-based distribution model may be difficult to implement, and we may not be able to commercialize this model if we do not comply with ongoing regulatory requirements; we may be subject to increased compliance risks as a result of our rapid growth, including our dependence on our direct sales force; we rely on a limited number of suppliers or, in some cases, single suppliers, for some of our laboratory instruments and materials and may not be able to find replacements or immediately transition to alternative suppliers; we may be unable to expand third-party payer coverage and reimbursement for Panorama and our other tests, or we may be required to refund reimbursements already received; third-party payers may withdraw coverage or provide lower levels of reimbursements due to changing policies, billing complexities or other factors; our estimates of total addressable market opportunity and forecasts of market growth may prove to be inaccurate, and even if the market in which we compete achieves the forecasted growth, our business could fail to grow at similar rates; and we are subject to litigation, which may require us to incur substantial costs, could divert the time and attention of our management and other employees and could result in substantial damages if unsuccessfully defended.

Additional risks and uncertainties that could affect Natera’s financial results are included under the captions, "Risk Factors" and "Management’s Discussion and Analysis of Financial Condition and Results of Operations" in Natera’s most recent filings on Forms 10-K and 10-Q and in other filings Natera makes with the SEC from time to time. These documents are available on Natera’s website at under the Investor Relations section and on the SEC’s website at


Natera, Inc.

Investor Relations
Mike Brophy, CFO, Natera, Inc., 650-249-9090

Barbara Sullivan, Sullivan & Associates, 714-374-6174, 

Natera, Inc.

Condensed Consolidated Balance Sheets


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Natera adopted Financial Accounting Standards Board Accounting Standards Update No. 2014-09 effective January 1, 2018 with full retrospective application to January 1, 2016. Results for periods prior to January 1, 2018 have been revised accordingly.


As of June 30, 2018, there were approximately 55,454,000 shares of common stock issued and outstanding.


Natera, Inc.

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Natera adopted Financial Accounting Standards Board Accounting Standards Update No. 2014-09 effective January 1, 2018 with full retrospective application to January 1, 2016. Results for periods prior to January 1, 2018 have been revised accordingly.


SOURCE Natera, Inc.

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