Panorama™ for your pregnancy
Panorama™, the most ordered NIPT, can assess conditions that can affect your baby’s health by doing a simple blood draw on you.1,2 A pregnant person’s blood contains DNA from them and also from their baby’s placenta. Panorama™ NIPT is a blood test performed during pregnancy that looks at the placental DNA to see if your baby has a high or low chance of having certain chromosomal conditions that could affect its health, along with providing your baby’s sex. Panorama™ delivers a personalized risk report to you and your clinician.
What to expect
CA residents: Find out more about how NIPT is offered under the California Prenatal Screening program and how Panorama can supplement it by clicking here.*
Understanding your results
Your report could state the following:
A low risk result means that the chance that your baby has one of the conditions tested by Panorama is very unlikely but not zero — less than 1 in 10,000 for most conditions.1,3
Panorama is a screening test, which means that this test does not make a final diagnosis. A high risk result means that your pregnancy has a higher chance of having a specific genetic condition. However, you cannot know for sure if your baby has that condition based on screening results alone.
If you receive a high risk Panorama result, speak with your healthcare provider (HCP) to discuss which next steps you could decide to pursue, such as genetic counseling, detailed ultrasound, and the option of diagnostic testing.
All medical decisions should be made after discussion with your HCP regarding diagnostic testing during the pregnancy, like chorionic villus sampling (CVS) or amniocentesis, or testing the baby after birth.
About 1 in 65 tests could receive a nonreportable result.3 You should speak with your HCP about these result types and whether you should consider having a second blood draw to do the test again. There is also a small chance that Panorama will have a result relating to your genetics or your physical health.1
1Natera internal data on file
2Definitive Healthcare report to identify billing for NIPT based on US Clearinghouse for Medical Claims using CPT codes 81420, 81507, 81422.
3Dar et al. Am J Obstet Gynecol. 2022 Aug;227(2):259.e1-259.e14.
4ACOG Practice Bulletin 226. Obstet Gynecol. 2020 Oct;136(4):859-867.
* CA residents: If your clinician ordered screening through the California Prenatal Screening program using Natera's Vasistera™ NIPT, Panorama™ will only screen for supplemental conditions. If this is the case, trisomies 21, 18 and 13, and fetal sex (optional) will be screened using Vasistera™ NIPT and will be reported separately.
** Not available for egg-donor or gestational carrier pregnancies or in cases of dizygotic (nonidentical) twins. Triploidy and microdeletions except for 22q11.2 deletions are not available for monozygotic (identical) twins.
† This test has been validated on full region deletions of Prader-Willi syndrome/Angelman syndrome (PWS/AS) only and might be unable to detect smaller deletions. It has not been validated for other molecular mechanisms which could cause PWS/AS such as uniparental disomy (UPD) or methylation.