Skip navigation

Innovations in women’s health genetic testing

From prenatal genetic testing that paved the way for earlier cancer recurrence testing, Natera is continuing to innovate its technology to broaden applications in women’s health that enable better health outcomes.

Hear from our CEO and medical director as they share Natera’s vision for transforming patient care.

Live webinar and Q&A
December 18
3pm PT/5pm CT

Innovations in women’s health genetic testing

From prenatal genetic testing that paved the way for earlier cancer recurrence testing, Natera is continuing to innovate its technology to broaden applications in women’s health that enable better health outcomes.

Hear from our CEO and medical director as they share Natera’s vision for transforming patient care.

Live webinar and Q&A
December 18
3pm PT/5pm CT

Pioneering NIPT technology now applied to cancer recurrence detection and monitoring

The unique SNP-based technology that distinguishes maternal from fetal cell-free DNA (cfDNA) has now been adapted to detect circulating tumor DNA (ctDNA) with Natera’s tumor-specific assay Signatera™. Cancer cells release ctDNA into the bloodstream, which can be measured to assess the presence of residual disease. This molecular residual disease test (MRD) is used to detect cancer recurrence and monitor treatment response.

Trusted expertise adapted to detect tumor DNA

See how Natera’s ctDNA test, Signatera™ works

Transforming management in women’s cancers

Signatera™, Natera’s molecular residual disease test (MRD), was the first tumor-specific assay for individualized cancer care. It enables earlier recurrence detection and ongoing surveillance in breast and gynecological cancers.

Icon

10.5 months earlier

median lead time in breast cancer recurrence detection over standard imaging1

Icon

2x the sensitivity

in detecting ovarian cancer relapse compared to CA-125, the most commonly used biomarker for ovarian cancer2,3

Icon

As early as 6 weeks

into treatment to identify response to immunotherapy in gynecologic cancers4

Impacting outcomes for women’s cancers

Angela’s Story

Like many patients, Angela has faced many questions throughout her journey with high risk breast cancer – what’s the next step in my treatment? Is the cancer ever going to come back? What’s causing this symptom?

Listen to the story of how she asked her doctor about Signatera™ to help monitor for recurrence and treatment response, giving her the peace of mind to move on with her life.

Most extensively validated MRD test

Signatera™ has published 65+ peer-reviewed studies across multiple indications, including colorectal, bladder, lung, breast, and gynecologic cancers.

“Detecting relapse before it becomes clinically symptomatic requires a test with high sensitivity and specificity. Signatera™ enables us to confidently identify patients with molecular relapse when the disease burden is so low that it is undetectable with imaging.”
Lajos Pusztai, MD, DPhil

Lajos Pusztai, MD, DPhil

Professor of Medicine (Medical Oncology); Co-Leader, Genetics, Genomics and Epigenetics Research Program, Yale Cancer Center, Yale School of Medicine

Most extensively validated MRD test

Signatera™ has published 65+ peer-reviewed studies across multiple indications, including colorectal, bladder, lung, breast, and gynecologic cancers.

“Detecting relapse before it becomes clinically symptomatic requires a test with high sensitivity and specificity. Signatera™ enables us to confidently identify patients with molecular relapse when the disease burden is so low that it is undetectable with imaging.”
Lajos Pusztai, MD, DPhil

Lajos Pusztai, MD, DPhil

Professor of Medicine (Medical Oncology); Co-Leader, Genetics, Genomics and Epigenetics Research Program, Yale Cancer Center, Yale School of Medicine

Investing in innovations in personalized genetic testing

R&D INVESTMENTS

400 MILLION

PEER-REVIEWED PUBLICATIONS

200+

PATIENT SAMPLES

10 MILLION

Source: Internal Natera Data

Learn more about Natera’s latest innovations

Natera would like to send you information about our products and services. You may unsubscribe from these communications at any time. By submitting your information you are agreeing to Natera's terms of use and privacy policy.

References

1Shaw JA, et al. Serial postoperative ctDNA monitoring for early detection of breast cancer recurrence. Poster presented at: ASCO; June 3-7, 2022; Chicago, IL.

2Hou et al. Gynecol Oncol. 2022; 167:334-341

3Chapman et al. Poster presented at 2021 AACR Annual Meeting.

4Bratman et al. Nature Cancer. 2020; 1(9):873-881.

icon-angle icon-bars icon-times