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Spectrum

Proven to boost IVF success

Spectrum preimplantation genetic testing (PGT) evaluates embryos for extra or missing chromosomes (PGT-A), single gene conditions (PGT-M), or structural rearrangements (PGT-SR), improving the chances of a healthy pregnancy.

Spectrum tests for chromosomal abnormalities and known inherited genetic condition(s). Sample collections include an embryo biopsy and parental blood/cheek swab. Most results will be returned to your doctor within 5-7 business days.

What is PGT-A and PGT-M?

PGT-A and PGT-M can improve the chance of a healthy pregnancy

PGT-A is a type of embryo screening that identifies embryos with extra or missing chromosomes, also called aneuploidy. For couples undergoing in vitro fertilization (IVF), identifying these embryos is important when selecting embryo(s) for transfer.

For individuals who know they are carriers of a single gene condition and are at risk for passing the condition on to their children, PGT-M can help identify unaffected embryo(s) for transfer.

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Why choose Spectrum?

Spectrum provides comprehensive preimplantation genetic testing (PGT). Across a range of maternal ages, pregnancy rates are higher when Spectrum PGT via single-nucleotide polymorphism (SNP) is performed with IVF.1

Spectrum SNP PGT can:1

  • Increase the chance of embryo implantation
  • Decrease the chance of miscarriage
  • Reduce the time to pregnancy
  • Reduce the chance of having a child with a chromosomal abnormality or single gene condition

Spectrum SNP PGT automatically confirms parentage of an embryo. Natera’s Parental Support™ bioinformatics technology uses genetic information from the biological parents to confirm embryo samples match the parental samples.

What is the Spectrum testing process?

PGT requires embryo biopsy, the removal of a small number of cells from the TE. The procedure is most commonly performed on days 5-6 when embryos reach the blastocyst stage of development.

The Spectrum embryo testing process is completed in conjunction with an IVF cycle:

 

  1. Eggs are fertilized and allowed to grow and develop into embryos.
  2. A biopsy performed with each of the developing embryo.
  3. Your embryo(s) remain at the IVF center and is cryopreserved, while biopsy samples are shipped to Natera.
  4. The samples are analyzed by Natera, and Spectrum results are sent to your IVF center.
  5. Your doctor determines which embryo (if any) is optimal for transfer to the uterus.

A blood, cheek, or sperm sample is required from BOTH biological parents in addition to the biopsy samples. Family member samples may also be requested for PGT-M. Natera provides complimentary mobile phlebotomy services and blood draw via local sites.

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Is Spectrum right for you?

We’re here to help you find out



References

1Simon et al. Fertil Steril. 2018;110(1):113-121