Spectrum Pre-implantation Genetics | Natera

Spectrum

Proven to help improve IVF success

Spectrum preimplantation genetic testing evaluates embryos for extra or missing chromosomes (PGT-A), structural rearrangements (PGT-SR), or single gene conditions (PGT-M).

Tests For:

Chromosome abnormalities and known familial genetic conditions

Collection Sample:

Embryo biopsy, blood draw/cheek swab

Turn Around Time:

5 - 7 days


Why use preimplantation testing?

Spectrum can improve the chance of a successful pregnancy while reducing the chance of miscarriage or of having a child with a chromosome condition. Spectrum can help identify the healthiest embryos during an IVF cycle.

Learn More: Download Brochure



Why choose Spectrum?

Spectrum supports you by offering:

  • PGT-A testing that can determine whether a chromosome abnormality originated from the mother or the father.
  • Screening for all chromosomes, haploidy, triploidy, and uniparental disomy (UPD).
  • Single-gene PGT-M testing includes 24-chromosome PGT-A testing.
  • Detection of DNA contamination and confirmation of parentage.
  • Calculated accuracy typically greater than 99%.


Spectrum supports you by offering:


Genetic Testing

24-chromosome preimplantation genetic testing for aneuploidy (PGT-A)

PGT-A evaluates the number of chromosomes in embryos created using IVF. Embryos with the normal number of chromosomes have a better chance of implanting and developing into a healthy pregnancy.

Preimplantation genetic testing for single gene conditions (PGT-M)

PGT-M testing can be performed as part of an IVF cycle. Available for couples identified as at-risk of having a child with a specific genetic dis­order, PGT-M predicts which embryos are affected or unaffected with specific genetic disorders. Couples can then use this information to select which embryos are transferred. Spectrum's single-gene PGT-M testing is performed concurrently with 24-chromosome PGT-A on a single embryo sample.

Preimplantation genetic testing for structural rearrangements (PGT-SR)

PGT-SR testing for inherited translocations or inversions can be performed as part of an IVF cycle. A person who carries a balanced chromosomal rearrangement may have an increased risk of passing on too little or too much genetic information to the embryo, possibly causing miscarriage, birth defects, or learning disabilities. Embryos can be tested for extra or missing chromosome pieces. Embryos with normal or balanced chromosome results are selected for transfer to the mother’s uterus.


The Spectrum process

Spectrum is used in conjunction with an IVF cycle. Embryos remain on-site at the patient’s IVF center. Cells are removed from an embryo and sent to Natera for genetic analysis. The following steps are included in the Spectrum process:

  1. A personalized IVF cycle is planned - eggs are fertilized and allowed to grow and develop into embryos.

  2. A biopsy of a few cells is removed from each of the developing embryos.

  3. Each embryo is cryopreserved while biopsy samples are shipped to Natera.

  4. Spectrum results are analyzed by Natera scientists and sent to your IVF center.

  5. Your physician determines which embryo (if any) is optimal for transfer to the uterus.