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How to Prepare for Your Next MRD Test: Practical Tips and FAQs

Undergoing an MRD test can be a significant step in your health journey and in monitoring your cancer. Being prepared can help reduce stress and ensure you get the most accurate and useful results. Here are some practical tips and frequently asked questions to guide you through the process.

Practical Tips for Preparation 

1. Understand the Test

    • Know the details: Make sure you know the name of the test (e.g., Signatera), what it is designed to measure (Minimal Residual Disease/circulating tumor DNA), and why your doctor has ordered it for your surveillance plan.

    • Write down questions: Before your appointment, prepare a list of questions for your healthcare team, such as:

      • Are there any dietary or medication restrictions before the test?

      • How and when will I receive the results?

      • Who should I contact if I have questions about the results?

2. Logistics and Scheduling

    • Confirm the appointment: Double-check the date, time, and location of the test.

    • Arrange transportation: If the test might make you feel tired or if you're taking any sedative medication that may impair your ability to drive, arrange for a friend or family member to drive you home.

    • Wear comfortable clothing: Choose clothing that allows easy access to the area of the body being tested (e.g., a short-sleeve shirt for a blood draw, which is typically how MRD tests are collected).

3. Review Insurance and Financials

    • Contact your insurer: Call your insurance provider beforehand to confirm coverage for the specific MRD test.

    • Ask about costs: Inquire about any potential out-of-pocket costs, co-pays, or deductibles. Natera's Patient Support team can also assist with benefit verification.

4. Bring Necessary Documents

    • Photo ID and insurance card: These are typically required for any medical appointment.

    • Doctor's order/requisition form: Have the paperwork from your referring physician ready.

    • Medication list: Bring an updated list of all medications, vitamins, and supplements you are currently taking.

Frequently Asked Questions (FAQs)

Q: How long will it take to get the results?

A: The turnaround time for results varies significantly depending on the lab and the complexity of the analysis. Be sure to ask your healthcare provider for an estimate during your appointment.

Q: Can I eat or drink before the test?

A: Blood draws for MRD testing typically do not require fasting. Always follow the specific pre-test instructions given to you by your doctor or the testing facility.

Q: Should I bring someone with me?

A: Yes, bringing a trusted friend or family member for support is often helpful. They can listen to and take notes on the information provided by the medical staff, especially when discussing the results or next steps in your care/surveillance plan.

Q: What if I feel anxious about the test?

A: It is completely normal to feel anxious about any health test, especially one related to recurrence monitoring. Communicate your feelings to your healthcare team—they can often offer reassurance or simple relaxation techniques. Focus on self-care, use deep breathing exercises, and remember that you are taking a proactive step in managing your health.