ASCO 2025 Posters and Presentations

Pancancer - Signatera Genome

Clinical performance of Signatera Genome assay in a cohort of patients with solid tumors

George M, Schwartz G, McHayleh W, et al. ASCO Annual Meeting 2025, Chicago, IL. May 30 - June 3, 2025.

Breast

Circulating tumor (ct)DNA monitoring of ER+/HER2- high-risk breast cancer during adjuvant endocrine therapy

Puzstai L, Scalise CB, Kalashnikova E, et al. Oral presentation presented at ASCO Annual Meeting 2025, Chicago, IL. May 30 - June 3, 2025.

Circulating tumor DNA (ctDNA) dynamics as a predictor of treatment response in metastatic breast cancer (mBC)

Razavi P, Cabel L, Teysir J, et al. Oral presentation presented at ASCO Annual Meeting 2025, Chicago, IL. May 30 - June 3, 2025.

Serial circulating tumor DNA (ctDNA) monitoring in early-stage, HR+/HER2-, invasive lobular carcinoma (ILC) of the breast and impact on clin

Foldi J, Rivero-Hinojosa S, Satta S, et al. ASCO Annual Meeting 2025, Chicago, IL. May 30 - June 3, 2025.

Cadence of circulating tumor DNA (ctDNA) testing for molecular surveillance in early-stage breast cancer (eBC)

Lipsyc-Sharf M, Cheng C, Medford A, et al. ASCO Annual Meeting 2025, Chicago, IL. May 30 - June 3, 2025.

Predicting nodal burden after neoadjuvant chemotherapy (NAC) with circulating tumor (ct)DNA for surgical planning: results from the I-SPY2 t

Mukhtar RA, Santos-Parker K, Santos-Parker J, et al. Oral presentation presented at ASCO Annual Meeting 2025, Chicago, IL. May 30 - June 3, 2025.

Circulating tumor DNA in patients with stage 2/3 HR+HER2-negative breast cancer receiving neoadjuvant endocrine therapy in the I-SPY2 Endocr

Alkhafaji S, Magbanua MJM, van ‘t Veer L, et al. Oral presentation presented at ASCO Annual Meeting 2025, Chicago, IL. May 30 - June 3, 2025.

I-SPY2 Endocrine Optimization Pilot (EOP): Neoadjuvant lasofoxifene in molecularly selected patients with hormone receptor positive (HR+)/HE

Wei M, Elias AD, Giridhar K, et al. ASCO Annual Meeting 2025, Chicago, IL. May 30 - June 3, 2025.

EORTC2129-BCG: elacestrant for treating ER+/HER2- breast cancer patients with ctDNA relapse (Treat ctDNA trial).

Ignatiadis M, Saloustros E, Joaquim A, et al. ASCO Annual Meeting 2025, Chicago, IL. M

MIBC

Circulating tumor DNA (ctDNA) in patients with muscle-invasive bladder cancer (MIBC) who received perioperative durvalumab (D) in NIAGARA

Powles T, van der Heijden MS, Wang Y, et al. Oral presentation presented at ASCO Annual Meeting 2025, Chicago, IL. May 30 - June 3, 2025.

UTUC

Association of Tumor-Informed ctDNA-based Molecular Residual Disease (MRD) with Clinical Outcomes for Upper Tract Urothelial Cancer (UTUC)

Ayanambakkam A, Laliotis G, Reyes K, et al. ASCO Annual Meeting 2025, Chicago, IL. May 30 - June 3, 2025.

Urothelial

Circulating tumor DNA monitoring in patients with advanced urothelial carcinoma treated with Enfortumab Vedotin +/- Pembrolizumab

Reyes KR, Jindal T, Mitchell B, et al. ASCO Annual Meeting 2025, Chicago, IL. May 30 - June 3, 2025.

Sarcoma

Early on-treatment ctDNA dynamics and response by imaging in patients with sarcoma

Victor A. ASCO Annual Meeting 2025, Chicago, IL. May 30 - June 3, 2025.

Early assessment of response to chemotherapy via ctDNA in soft tissue sarcoma

Zhou M, Nam Bui N, Pan M, et al. ASCO Annual Meeting 2025, Chicago, IL. May 30 - June 3, 2025.

Anal

Circulating tumor DNA as an early response indicator in anal squamous cell carcinoma treated with chemoradiation

Bercz A, Alvarez J, Kostrzewa CE, et al. Oral presentation presented at ASCO Annual Meeting 2025, Chicago, IL. May 30 - June 3, 2025.

CRC

Impact of Perioperative Complications on MRD Detection and Prognosis Using ctDNA: Insights from the GALAXY Study

Oki E, Sato S, Ando K, et al. ASCO Annual Meeting 2025, Chicago, IL. May 30 - June 3, 2025.

Development of a methylation-based, tissue-free test for the detection of molecular residual disease by circulating tumor DNA

Shen JPYC, Reiter JR, Babiarz J, et al. ASCO Annual Meeting 2025, Chicago, IL. May 30 - June 3, 2025.

A precision medicine trial leveraging tissue and blood-based tumor genomics to optimize treatment in resected stage III and high-risk stage

Montagut M, Tamberi S, Leone F, et al. ASCO Annual Meeting 2025, Chicago, IL. May 30 - June 3, 2025.

RWE CRC

Exome analysis of over 5000 esophagogastric cancers

Mukherji R, Aushev VN, Rivero-Hinojosa S, et al. ASCO Annual Meeting 2025, Chicago, IL. May 30 - June 3, 2025.

ctDNA dynamics and targeted therapies associated with genetic mutations in patients with colorectal cancer

Malla M, Aushev VN, Ramu A, et al. ASCO Annual Meeting 2025, Chicago, IL. May 30 - June 3, 2025.

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