Our Technology | Natera

Experts in cell-free DNA

Natera core technology and finely tuned workflows cut through the noise to deliver superior clinical and analytical performance.


DNA Extraction

Efficiently extracts high quality cfDNA to remove impurities, reduce noise, and produce significantly higher yield than traditional methods to increase consistency in results.

Custom Library Preparation

Reduces background noise and variability in the cfDNA sample.

Target > 13,000 SNPs

Curated, informative, and pan-ethnic SNPs address population variability (including ethnicity and donor-recipient relatedness).

Proprietary Bioinformatics

Provide precise, highly accurateresults based on our deep experience in cfDNA.

Applications in women's health, cancer, and organ transplantation.

Watch Applications in cell-free DNA, presented by Paul Billings at the ASHI BANFF Conference.

Natera is harnessing the power of cell-free DNA from a single blood sample and a methodology that uses single-nucleotide polymorphisms (SNPs) for
non-invasive testing.

Natera’s Constellation Platform

Constellation allows laboratories worldwide to access key technologies that Natera uses in its own lab. Partner labs now have the opportunity to develop, validate, and clinically offer complex genomics assays in their own facilities.

The Constellation™ platform helps labs in more than 15 countries implement next-generation clinical genomic testing. Constellation’s applications focus on the analysis of cell-free DNA, mixture fraction, and heterogeneous mixtures of DNA, including:

  • Liquid biopsy applications in oncology (in development) 
  • Research tools and algorithms for genomic analysis
  • Non-invasive prenatal testing (NIPT)
  • NIPT paternity testing
  • Fetal fraction analysis

Case Study: Genetica

Case Study Lifelabs

Download: Constellation Brochure


With Constellation, we offer exceptional services and support.

  • Dedicated scientific staff to support site preparation and workflow customization
  • Certification program to recognize laboratory, operator, and process quality 
  • Field-based technical support team for on-market support
  • Step-by-step implementation program with live training
  • Assistance in procurement of validation samples
  • Natera branding and global marketing programs
  • Dedicated software integration team

Is Constellation right for you?

We're here to help you find out.

Schedule a call