Vistara NIPT Single Gene Test | Single Gene Disorders Testing

Vistara

Most comprehensive prenatal single-gene screening test

Vistara identifies risk for single-gene disorders that may have otherwise gone undetected prenatally

Tests For:

25 serious genetic conditions

Collection Sample:

Blood draw

Turn Around Time:

2-3 weeks


Vistara screens cell-free DNA (cfDNA) for serious genetic conditions that affect quality of life and may benefit from medical and/or surgical intervention.


Screened conditions include:

  • Noonan syndrome
  • Achondroplasia
  • Osteogenesis imperfecta
  • Rett syndrome
  • And 21 other single-gene disorders across 30 genes

See all conditions

Conditions screened by Vistara have a combined incidence of 1 in 600 – higher than that of Down syndrome.


Vistara has a combined analytical sensitivity and specificity of >99% in validation studies and no known false positives in commercial experience.

 

Vistara identifies risk for clinically relevant conditions that may have otherwise gone undetected until after birth or into childhood.

Identifies early in pregnancy the risk for clinically relevant conditions that may go undetected until after birth or into childhood:

  • Ultrasound findings are not a reliable indicator.
  • Traditional NIPTs do not screen for these conditions.
  • Invasive testing (microarray) does not ensure a diagnosis.
  • Patient or family history are typically not good indicators of risk.

Vistara prenatal screening can lead to improved delivery management and targeted neonatal care.


Noonan
syndrome

Clinical actions

  • Fetal echocardiogram
  • Labor and delivery management
  • Early assessment for learning differences

Achondroplasia
 

Clinical actions

  • Labor and delivery management
  • Monitor for spinal stenosis
  • Early sleep studies to reduce risk of SIDS

Osteogenesis imperfecta

Clinical actions

  • Labor and delivery management to avoid fractures
  • Neonatal care
  • Early recognition and treatment of fractures

 

How Does Vistara Single-Gene Testing Differ From Other Types of Prenatal Testing?

Vistara is the next step in the evolution of NIPT, going beyond chromosome-level anomalies to assess single gene disorders. Vistara can be used in conjunction with Panorama NIPT to provide a more comprehensive screening of clinically serious genetic disorders, as traditional NIPT’s do not screen for these conditions. In addition, Vistara can be used as an adjunct to a CVS or amniocentesis as invasive diagnostic testing such as a karyotype or microarray, does not evaluate for single gene disorders.

 

Consider Vistara for the following indications: