What is Spectrum®?

Spectrum preimplantation genetic screening (PGS) evaluates embryos for extra or missing chromosomes. PGS is an option for any in vitro fertilization (IVF) patient. Spectrum preimplantation genetic diagnosis (PGD) tests embryos for specific inherited genetic disorders.

 

Why use preimplantation testing?

Spectrum can improve the chance of a successful pregnancy while reducing the chance of miscarriage or of having a child with a chromosome condition. Spectrum can help identify the healthiest embryos during an IVF cycle.

 

Download Brochure

Why use preimplantation testing?

Spectrum can improve the chance of a successful pregnancy while reducing the chance of miscarriage or of having a child with a chromosome condition. Spectrum can help identify the healthiest embryos during an IVF cycle.

 

Download Brochure

Why use preimplantation testing?

Spectrum can improve the chance of a successful pregnancy while reducing the chance of miscarriage or of having a child with a chromosome condition. Spectrum can help identify the healthiest embryos during an IVF cycle.

 

Download Brochure

Why use preimplantation testing?

Spectrum can improve the chance of a successful pregnancy while reducing the chance of miscarriage or of having a child with a chromosome condition. Spectrum can help identify the healthiest embryos during an IVF cycle.

 

Download Brochure

Spectrum PGS what does it screen for article

Testing for many possibilities

24-chromosome screening

24-chromosome preimplantation genetic screening (PGS) evaluates the number of chromosomes in embryos created using IVF. Embryos with the normal number of chromosomes have a better chance of implanting and developing into a healthy pregnancy.

Single-gene testing

Single-gene preimplantation genetic diagnosis (PGD) testing can be performed as part of an IVF cycle. Available for couples identified as at-risk of having a child with a specific genetic dis­order, PGD predicts which embryos are affected or unaffected with specific genetic disorders. Couples can then use this information to select which embryos are transferred. Spectrum's single-gene PGD testing is performed concurrently with 24-chromosome PGS on a single embryo sample.

Translocation and Inversion testing

Translocation and inversion PGD testing can be performed as part of an IVF cycle. A person who carries a balanced chromosomal rearrangement may have an increased risk of passing on too little or too much genetic information to the embryo, possibly causing miscarriage, birth defects, or learning disabilities. Embryos can be tested for extra or missing chromosome pieces. Embryos with normal or balanced chromosome results are selected for transfer to the mother’s uterus.

 

Why choose Spectrum?

Spectrum supports you by offering:

  • calculated accuracy that is greater than 99%.
  • screening for all chromosomes.
  • screening for haploidy, triploidy, and uniparental disomy (UPD).
  • PGS testing that can determine whether a chromosome abnormality originated from the mother or the father.
  • single-gene PGD testing includes 24-chromosome PGS testing.
  • detection of DNA contamination and confirmation of parentage.

The Spectrum process

Spectrum is used in conjunction with an IVF cycle. Embryos remain on-site at the patient’s IVF center. Cells are removed from an embryo and sent to Natera for genetic analysis. The following steps are included in the Spectrum process:

  1. A personalized IVF cycle is planned and eggs are retrieved and inseminated.
  2. The fertilized eggs are allowed to grow and develop into embryos.
  3. Embryo biopsy is performed by an embryologist who removes one cell at the cleavage stage (day 3) or — more commonly — a few cells at the blastocyst stage (day 5/6) from each of the developing embryos.
  4. Each embryo is cryopreserved while biopsy samples are shipped to Natera's certified laboratory via medical courier.
  5. Our expert team of scientists perform genetic analysis on each sample that we receive.
  6. The Spectrum results are returned to the IVF center.
  7. The IVF physician reviews the Spectrum results and the embryo development to determine which embryos (if any) are optimal for transfer to the uterus.
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