Diseases

Natera tests screen for 35 of the nearly 80 diseases that can be treated with cord blood

Cancers

  • Acute lymphoblastic leukemia (ALL)
  • Acute myelogenous leukemia (AML)
  • Chronic lymphocytic leukemia (CML)
  • Hodgkin’s lymphoma (HL)
  • Juvenile myelomonocytic leukemia (JMML)
  • Lymphomatoid granulomatosis
  • Non-Hodgkin’s lymphoma (NHL)

Blood disorders

  • E-β+ thalassemia
  • E-βo thalassemia
  • HbSC disease
  • Sickle βo thalassemia
  • Sickle-cell anemia
  • α-thalassemia major
  • β-thalassemia intermedia
  • β-thalassemia major

Metabolic disorders

  • Adrenoleukodystrophy
  • Alpha-mannosidosis
  • Gaucher disease
  • Hermansky-Pudlak syndrome
  • Hunter syndrome
  • Hurler syndrome
  • Hurler-Scheie/Scheie syndromes
  • Krabbe disease
  • Maroteaux-Lamy syndrome
  • Metachromatic leukodystrophy
  • Morquio syndrome
  • Mucolipidosis type II
  • Niemann Pick syndrome type A/B
  • Sandhoff disease
  • Sanfilippo syndrome
  • Tay-Sachs disease
  • Gunther disease
  • Sly syndrome

Bone marrow failure disorders

  • Amegakaryocytic thrombocytopenia
  • Autoimmune neutropenia (severe)
  • Dyskeratosis congenita
  • Fanconi anemia
  • Congenital dyserythropoietic anemia
  • Congenital sideroblastic anemia
  • Cyclic neutropenia
  • Diamond-Blackfan anemia
  • Evans syndrome
  • Glanzmann disease
  • Juvenile dermatomyositis
  • Kostmann syndrome
  • Myelodysplastic syndromes
  • Pancytopenia
  • Red cell aplasia
  • Refractory anemia
  • Severe aplastic anemia
  • Severe neonatal thrombocytopenia
  • Shwachman-Diamond syndrome
  • Thrombocytopenia with absent radius (TAR syndrome)

Immune disorders

  • Adenosine deaminase deficiency
  • Ataxia telangiectasia
  • Chronic granulomatous disease
  • Complete DiGeorge syndrome*
  • Omenn syndrome
  • Severe combined immunodeficiency (SCID)
  • Autoimmune lymphoproliferative syndrome
  • Hemophagocytic lymphohistiocytosis
  • IKK gamma deficiency
  • Immune dysregulation polyendocrinopathy
  • Juvenile xanthogranulomas
  • Langerhans cell histiocytosis
  • Leukocyte adhesion deficiency
  • Myelokathexis
  • Reticular dysplasia
  • Thymic dysplasia
  • Wiskott-Aldrich syndrome
  • X-linked agammaglobulinemia
  • X-linked immunodeficiency
  • X-linked lymphoproliferative disease

Other

  • Osteopetrosis
  • Systemic mastocytosis

All highlighted diseases are screened by Natera products. *Approximately 50% of cases are caused by a 22q11.2 deletion.